BREXIT: Hot topic
Worried about Brexit fallout on chemicals regulation?
Find what experts have to say on this topic. Learn how to prepare for all potential Brexit outcomes.

3.5.5.: Additional classification considerations

It is increasingly accepted that the process of chemical-induced tumorigenesis in humans and animals involves genetic changes for example in proto-oncogenes and/or tumour suppresser genes of somatic cells. Therefore, the demonstration of mutagenic properties of substances in somatic and/or germ cells of mammals in vivo may have implications for the potential classification of these substances as carcinogens (see also Carcinogenicity, section 3.6, paragraph 3.6.2.2.6).